Publications
2020
Papers in international journals
- M. Hermsen, B. Smeets, L. Hilbrands and J. van der Laak, "Artificial intelligence; is there a potential role in nephropathology?", Nephrology Dialysis Transplantation, 2020.
- Z. Swiderska-Chadaj, K. Hebeda, M. van den Brand and G. Litjens, "Artificial intelligence to detect MYC translocation in slides of diffuse large B-cell lymphoma", Virchows Archiv, 2020.
- Z. Swiderska-Chadaj, T. de Bel, L. Blanchet, A. Baidoshvili, D. Vossen, J. van der Laak and G. Litjens, "Impact of rescanning and normalization on convolutional neural network performance in multi-center, whole-slide classification of prostate cancer", Scientific Reports, 2020;10(1):14398.
- H. Pinckaers, B. van Ginneken and G. Litjens, "Streaming convolutional neural networks for end-to-end learning with multi-megapixel images", IEEE Transactions on Pattern Analysis and Machine Intelligence, 2020.
- W. Bulten, M. Balkenhol, J. Belinga, A. Brilhante, A. Çakır, L. Egevad, M. Eklund, X. Farré, K. Geronatsiou, V. Molinié, G. Pereira, P. Roy, G. Saile, P. Salles, E. Schaafsma, J. Tschui, A. Vos, B. Delahunt, H. Samaratunga, D. Grignon, A. Evans, D. Berney, C. Pan, G. Kristiansen, J. Kench, J. Oxley, K. Leite, J. McKenney, P. Humphrey, S. Fine, T. Tsuzuki, M. Varma, M. Zhou, E. Comperat, D. Bostwick, K. Iczkowski, C. Magi-Galluzzi, J. Srigley, H. Takahashi, T. van der Kwast, H. van Boven, R. Vink, J. van der Laak, C. der Hulsbergen-van Kaa and G. Litjens, "Artificial Intelligence Assistance Significantly Improves Gleason Grading of Prostate Biopsies by Pathologists", Modern Pathology, 2020.
- G. van Leenders, T. van der Kwast, D. Grignon, A. Evans, G. Kristiansen, C. Kweldam, G. Litjens, J. McKenney, J. Melamed, N. Mottet, G. Paner, H. Samaratunga, I. Schoots, J. Simko, T. Tsuzuki, M. Varma, A. Warren, T. Wheeler, S. Williamson, K. Iczkowski and I. Members, "The 2019 International Society of Urological Pathology (ISUP) Consensus Conference on Grading of Prostatic Carcinoma.", American Journal of Surgical Pathology, 2020;44(8):e87-e99.
- Z. Kos, A. Roblin, R. Kim, S. Michiels, B. Gallas, W. Chen, K. van de Vijver, S. Goel, S. Adams, S. Demaria, G. Viale, T. Nielsen, S. Badve, W. Symmans, C. Sotiriou, D. Rimm, S. Hewitt, C. Denkert, S. Loibl, S. Luen, J. Bartlett, P. Savas, G. Pruneri, D. Dillon, M. Cheang, A. Tutt, J. Hall, M. Kok, H. Horlings, A. Madabhushi, J. van der Laak, F. Ciompi, A. Laenkholm, E. Bellolio, T. Gruosso, S. Fox, J. Araya, G. Floris, J. Hudeček, L. Voorwerk, A. Beck, J. Kerner, D. Larsimont, S. Declercq, G. den Eynden, L. Pusztai, A. Ehinger, W. Yang, K. AbdulJabbar, Y. Yuan, R. Singh, C. Hiley, M. al Bakir, A. Lazar, S. Naber, S. Wienert, M. Castillo, G. Curigliano, M. Dieci, F. André, C. Swanton, J. Reis-Filho, J. Sparano, E. Balslev, I. Chen, E. Stovgaard, K. Pogue-Geile, K. Blenman, F. Penault-Llorca, S. Schnitt, S. Lakhani, A. Vincent-Salomon, F. Rojo, J. Braybrooke, M. Hanna, M. Soler-Monsó, D. Bethmann, C. Castaneda, K. Willard-Gallo, A. Sharma, H. Lien, S. Fineberg, J. Thagaard, L. Comerma, P. Gonzalez-Ericsson, E. Brogi, S. Loi, J. Saltz, F. Klaushen, L. Cooper, M. Amgad, D. Moore and R. Salgado, "Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer", npj Breast Cancer, 2020;6(1).
- M. Amgad, A. Stovgaard, E. Balslev, J. Thagaard, W. Chen, S. Dudgeon, A. Sharma, J. Kerner, C. Denkert, Y. Yuan, K. AbdulJabbar, S. Wienert, P. Savas, L. Voorwerk, A. Beck, A. Madabhushi, J. Hartman, M. Sebastian, H. Horlings, J. Hudeček, F. Ciompi, D. Moore, R. Singh, E. Roblin, M. Balancin, M. Mathieu, J. Lennerz, P. Kirtani, I. Chen, J. Braybrooke, G. Pruneri, S. Demaria, S. Adams, S. Schnitt, S. Lakhani, F. Rojo, L. Comerma, S. Badve, M. Khojasteh, W. Symmans, C. Sotiriou, P. Gonzalez-Ericsson, K. Pogue-Geile, R. Kim, D. Rimm, G. Viale, S. Hewitt, J. Bartlett, F. Penault-Llorca, S. Goel, H. Lien, S. Loibl, Z. Kos, S. Loi, M. Hanna, S. Michiels, M. Kok, T. Nielsen, A. Lazar, Z. Bago-Horvath, L. Kooreman, J. van der Laak, J. Saltz, B. Gallas, U. Kurkure, M. Barnes, R. Salgado and L. Cooper, "Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group", npj Breast Cancer, 2020;6(1).
- M. Balkenhol, W. Vreuls, C. Wauters, S. Mol, J. van der Laak and P. Bult, "Histological subtypes in triple negative breast cancer are associated with specific information on survival", Annals of Diagnostic Pathology, 2020;46:151490.
- W. Bulten, H. Pinckaers, H. van Boven, R. Vink, T. de Bel, B. van Ginneken, J. van der Laak, C. de Hulsbergen-van Kaa and G. Litjens, "Automated deep-learning system for Gleason grading of prostate cancer using biopsies: a diagnostic study", Lancet Oncology, 2020;21(2):233-241.
- F. Ayatollahi, S. Shokouhi and J. Teuwen, "Differentiating Benign and Malignant Mass and non-Mass Lesions in Breast DCE-MRI using Normalized Frequency-based Features", International Journal of Computer Assisted Radiology and Surgery, 2020;15(2):297-307.
Preprints
- C. Mercan, M. Balkenhol, R. Salgado, M. Sherman, P. Vielh, W. Vreuls, A. Polonia, H. Horlings, W. Weichert, J. Carter, P. Bult, M. Christgen, C. Denkert, K. van de Vijver, J. van der Laak and F. Ciompi, "Automated Scoring of Nuclear Pleomorphism Spectrum with Pathologist-level Performance in Breast Cancer", arXiv:2012.04974, 2020.
Papers in conference proceedings
- Z. Swiderska-Chadaj, K. Nurzynska, G. Bartlomiej, K. Grunberg, L. van der Woude, M. Looijen-Salamon, A. Walts, T. Markiewicz, F. Ciompi and A. Gertych, "A deep learning approach to assess the predominant tumor growth pattern in whole-slide images of lung adenocarcinoma", Medical Imaging, 2020;11320:113200D.
- C. Mercan, G. Reijnen-Mooij, D. Martin, J. Lotz, N. Weiss, M. van Gerven and F. Ciompi, "Virtual staining for mitosis detection in Breast Histopathology", IEEE International Symposium on Biomedical Imaging, 2020:1770-1774.
- J. Linmans, J. van der Laak and G. Litjens, "Efficient Out-of-Distribution Detection in Digital Pathology Using Multi-Head Convolutional Neural Networks", Medical Imaging with Deep Learning, 2020:465-478.
- K. Faryna, F. Tushar, V. D'Anniballe, R. Hou, G. Rubin and J. Lo, "Attention-guided classification of abnormalities in semi-structured computed tomography reports", Medical Imaging, 2020;11314:397 - 403.
- Z. Swiderska-Chadaj, K. Hebeda, M. van den Brand and G. Litjens, "Predicting MYC translocation in HE specimens of diffuse large B-cell lymphoma through deep learning", Medical Imaging, 2020;11320:1132010.
- A. Saha, F. Tushar, K. Faryna, V. D'Anniballe, R. Hou, M. Mazurowski, G. Rubin and J. Lo, "Weakly Supervised 3D Classification of Chest CT using Aggregated Multi-Resolution Deep Segmentation Features", Medical Imaging, 2020;11314:39 - 44.
- Z. Swiderska-Chadaj, E. Stoelinga, A. Gertych and F. Ciompi, "Multi-Patch Blending improves lung cancer growth pattern segmentation in whole-slide images", IEEE International Conference on Computational Problems of Electrical Engineering, 2020.
- K. Faryna, K. Koschmieder, M. Paul, T. van den Heuvel, A. van der Eerden, R. Manniesing and B. van Ginneken, "Adversarial cycle-consistent synthesis of cerebral microbleeds for data augmentation", Medical Imaging Meets NeurIPS Workshop - 34th Conference on Neural Information Processing Systems (NeurIPS), 2020.
- D. Tellez, D. Hoppener, C. Verhoef, D. Grunhagen, P. Nierop, M. Drozdzal, J. van der Laak and F. Ciompi, "Extending Unsupervised Neural Image Compression With Supervised Multitask Learning", Medical Imaging with Deep Learning, 2020.
- L. van Eekelen, H. Pinckaers, K. Hebeda and G. Litjens, "Multi-class semantic cell segmentation and classification of aplasia in bone marrow histology images", Medical Imaging, 2020;11320:113200B.
Abstracts
- J. Bokhorst, F. Ciompi, I. Zlobec, A. Lugli, M. Vieth, R. Kirsch, J. van der Laak and I. Nagtegaal, "Computer-assisted hot-spot selection for tumor budding assessment in colorectal cancer", European Congress of Pathology, 2020.
- L. Studer, J. Bokhorst, I. Zlobec, A. Lugli, A. Fischer, F. Ciompi, J. van der Laak, I. Nagtegaal and H. Dawson, "Validation of computer-assisted tumour-bud and T-cell detection in pT1 colorectal cancer", European Congress of pathology, 2020.
- M. Balkenhol, P. Bult, D. Tellez, W. Vreuls, P. Clahsen, F. Ciompi and J. der Laak, "Deep learning enables fully automated mitotic density assessment in breast cancer histopathology", European Journal of Cancer, 2020.
- C. Mercan, M. Balkenhol, J. Laak and F. Ciompi, "Grading nuclear pleomorphism in breast cancer using deep learning", European Congress of Pathology, 2020.
- J. Bokhorst, I. Nagtegaal, I. Zlobec, A. Lugli, M. Vieth, R. Kirsch, J. van der Laak and F. Ciompi, "Deep learning based tumor bud detection in pan-cytokeratin stained colorectal cancer whole-slide images", European Congress of Pathology, 2020.
- T. Haddad, J. Bokhorst, L. van den Dobbelsteen, F. Simmer, J. van der Laak and I. Nagtegaal, "Characterisation of the tumour-host interface as a prognostic factor through deep learning systems", United European Gastroenterology Journal, 2020.
PhD theses
- M. Balkenhol, "Tissue-based biomarker assessment for predicting prognosis of triple negative breast cancer: the additional value of artificial intelligence", PhD thesis, 2020.
Master theses
- L. van Eekelen, "Deep learning-based analysis of bone marrow histopathology images", Master thesis, 2020.
- J. Spronck, "Multi conditional lung nodule synthesis for improved nodule malignancy classification in Computed Tomography scans", Master thesis, 2020.
- K. Faryna, "Brain MRI synthesis via pathology factorization and adversarial cycle-consistent learning for data augmentation", Master thesis, 2020.
- T. Payer, "AI-assisted PD-L1 scoring in non-small-cell lung cancer", Master thesis, 2020.